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Effects of STI571 (gleevec) on pancreatic cancer cell growth

BACKGROUND: Pancreatic cancer is an aggressive malignancy characterized by low responsiveness to chemotherapy and radiotherapy. This resistance is partly due to the overexpression of several tyrosine kinase receptors and their ligands. STI571 has specific activity in inhibiting c-kit, PDGF and Abl r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Junsheng, Kleeff, Jörg, Guo, Junchao, Fischer, Lars, Giese, Nathalia, Büchler, Markus W, Friess, Helmut
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC212230/
https://ncbi.nlm.nih.gov/pubmed/14521721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-2-32
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