Effects of STI571 (gleevec) on pancreatic cancer cell growth

BACKGROUND: Pancreatic cancer is an aggressive malignancy characterized by low responsiveness to chemotherapy and radiotherapy. This resistance is partly due to the overexpression of several tyrosine kinase receptors and their ligands. STI571 has specific activity in inhibiting c-kit, PDGF and Abl r...

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Autors principals: Li, Junsheng, Kleeff, Jörg, Guo, Junchao, Fischer, Lars, Giese, Nathalia, Büchler, Markus W, Friess, Helmut
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2003
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC212230/
https://ncbi.nlm.nih.gov/pubmed/14521721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-2-32
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