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Effects of STI571 (gleevec) on pancreatic cancer cell growth
BACKGROUND: Pancreatic cancer is an aggressive malignancy characterized by low responsiveness to chemotherapy and radiotherapy. This resistance is partly due to the overexpression of several tyrosine kinase receptors and their ligands. STI571 has specific activity in inhibiting c-kit, PDGF and Abl r...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC212230/ https://ncbi.nlm.nih.gov/pubmed/14521721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-2-32 |
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