Effects of STI571 (gleevec) on pancreatic cancer cell growth

BACKGROUND: Pancreatic cancer is an aggressive malignancy characterized by low responsiveness to chemotherapy and radiotherapy. This resistance is partly due to the overexpression of several tyrosine kinase receptors and their ligands. STI571 has specific activity in inhibiting c-kit, PDGF and Abl r...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Junsheng, Kleeff, Jörg, Guo, Junchao, Fischer, Lars, Giese, Nathalia, Büchler, Markus W, Friess, Helmut
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2003
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC212230/
https://ncbi.nlm.nih.gov/pubmed/14521721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-2-32
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