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Mutations in HIV reverse transcriptase which alter RNase H activity and decrease strand transfer efficiency are suppressed by HIV nucleocapsid protein

Structural studies of authentic HIV reverse transcriptase (RT) suggest a role for the p51 carboxyl terminus in forming an active RNase H conformation [Rodgers, D. W., Gamblin, S. J., Harris, B. A., Ray, S., Culp, J. S., Hellmig, B., Woolf, D. J., Debouck, C. & Harrison, S. C. (1995) Proc. Natl....

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Autors principals: Cameron, Craig E., Ghosh, Madhumita, Le Grice, Stuart F. J., Benkovic, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21221/
https://ncbi.nlm.nih.gov/pubmed/9192628
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