c-Myc transactivation of LDH-A: Implications for tumor metabolism and growth

Cancer cells are able to overproduce lactic acid aerobically, whereas normal cells undergo anaerobic glycolysis only when deprived of oxygen. Tumor aerobic glycolysis was recognized about seven decades ago; however, its molecular basis has remained elusive. The lactate dehydrogenase-A gene (LDH-A),...

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Bibliografske podrobnosti
Main Authors: Shim, Hyunsuk, Dolde, Christine, Lewis, Brian C., Wu, Chyi-Sun, Dang, Gerard, Jungmann, Richard A., Dalla-Favera, Riccardo, Dang, Chi V.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1997
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC21214/
https://ncbi.nlm.nih.gov/pubmed/9192621
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