c-Myc transactivation of LDH-A: Implications for tumor metabolism and growth

Cancer cells are able to overproduce lactic acid aerobically, whereas normal cells undergo anaerobic glycolysis only when deprived of oxygen. Tumor aerobic glycolysis was recognized about seven decades ago; however, its molecular basis has remained elusive. The lactate dehydrogenase-A gene (LDH-A),...

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Detaylı Bibliyografya
Asıl Yazarlar: Shim, Hyunsuk, Dolde, Christine, Lewis, Brian C., Wu, Chyi-Sun, Dang, Gerard, Jungmann, Richard A., Dalla-Favera, Riccardo, Dang, Chi V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences of the USA 1997
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC21214/
https://ncbi.nlm.nih.gov/pubmed/9192621
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