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MYC, Metabolism, Cell Growth, and Tumorigenesis
The MYC proto-oncogene is frequently activated in human cancers through a variety of mechanisms. Its deregulated expression, unconstrained by inactivation of key checkpoints, such as p53, contributes to tumorigenesis. Unlike its normal counterpart, which is restrained by negative regulators, the unl...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3721271/ https://ncbi.nlm.nih.gov/pubmed/23906881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014217 |
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