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Anti-CD2 antibodies induce T cell unresponsiveness in vivo

The CD2 receptor functions as an adhesion and signal molecule in T cell recognition. Multimeric binding of CD2 on T cells to its physiologic ligand LFA-3 on cognate partner cells in vitro efficiently augments the antigen-specific T cell signal delivered by the T cell receptor/CD3 complex. The precis...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1991
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118978/
https://ncbi.nlm.nih.gov/pubmed/1682413
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