The anti-CD2 monoclonal antibody BTI-322 generates unresponsiveness by activation-associated T cell depletion

The antihuman CD2 MoAb BTI-322 (Lo-CD2a) effectively inhibits T cell responses in vitro to allogeneic cells, which is followed by unresponsiveness to the original stimulator in secondary stimulation. We studied the xenogeneic human antiporcine mixed lymphocyte reaction (MLR), and utilized anti-T cel...

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Bibliographic Details
Main Authors: XU, Y, KOLBER-SIMONDS, D, HOPE, J A, BAZIN, H, LATINNE, D, MONROY, R, WHITE-SCHARF, M E, SCHUURMAN, H-J
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2004
Subjects:
Basic Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809246/
https://ncbi.nlm.nih.gov/pubmed/15544625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02650.x
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