Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells

Growth factor-derived mitogenic signals from the cell surface are transmitted to the nucleus via receptor tyrosine kinases (RTKs), the adaptor proteins Shc and Grb2, and a Ras-dependent protein kinase cascade that activates the extracellular signal regulated kinase (ERK) subfamily of mitogen-activat...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Herrlich, Andreas, Daub, Henrik, Knebel, Axel, Herrlich, Peter, Ullrich, Axel, Schultz, Günter, Gudermann, Thomas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 1998
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC21189/
https://ncbi.nlm.nih.gov/pubmed/9671791
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