Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells

Growth factor-derived mitogenic signals from the cell surface are transmitted to the nucleus via receptor tyrosine kinases (RTKs), the adaptor proteins Shc and Grb2, and a Ras-dependent protein kinase cascade that activates the extracellular signal regulated kinase (ERK) subfamily of mitogen-activat...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Herrlich, Andreas, Daub, Henrik, Knebel, Axel, Herrlich, Peter, Ullrich, Axel, Schultz, Günter, Gudermann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC21189/
https://ncbi.nlm.nih.gov/pubmed/9671791
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares