Repression of interleukin-4 in T helper type 1 cells by Runx/Cbfβ binding to the Il4 silencer

Interferon γ (IFNγ) is the hallmark cytokine produced by T helper type 1 (Th1) cells, whereas interleukin (IL)-4 is the hallmark cytokine produced by Th2 cells. Although previous studies have revealed the roles of cytokine signaling and of transcription factors during differentiation of Th1 or Th2 c...

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Библиографические подробности
Главные авторы: Naoe, Yoshinori, Setoguchi, Ruka, Akiyama, Kaori, Muroi, Sawako, Kuroda, Masahiko, Hatam, Farah, Littman, Dan R., Taniuchi, Ichiro
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2007
Предметы:
Brief Definitive Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118685/
https://ncbi.nlm.nih.gov/pubmed/17646405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062456
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