Lataa...
MK2 controls the level of negative feedback in the NF-κB pathway and is essential for vascular permeability and airway inflammation
We demonstrate that mitogen-activated protein kinase–activated kinase-2 (MK2) is essential for localized Th2-type inflammation and development of experimental asthma. MK2 deficiency does not affect systemic Th2 immunity, but reduces endothelial permeability, as well as adhesion molecule and chemokin...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Rockefeller University Press
2007
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118652/ https://ncbi.nlm.nih.gov/pubmed/17576778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062621 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|