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Inhibiting pollen reduced nicotinamide adenine dinucleotide phosphate oxidase–induced signal by intrapulmonary administration of antioxidants blocks allergic airway inflammation

BACKGROUND: Ragweed extract (RWE) contains NADPH oxidases that induce oxidative stress in the airways independent of adaptive immunity (signal 1) and augment antigen (signal 2)–induced allergic airway inflammation. OBJECTIVE: To test whether inhibiting signal 1 by administering antioxidants inhibits...

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Main Authors: Dharajiya, Nilesh, Choudhury, Barun K., Bacsi, Attila, Boldogh, Istvan, Alam, Rafeul, Sur, Sanjiv
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042252/
https://ncbi.nlm.nih.gov/pubmed/17336614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2006.11.634
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