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Increased susceptibility to colitis and colorectal tumors in mice lacking core 3–derived O-glycans

Altered intestinal O-glycan expression has been observed in patients with ulcerative colitis and colorectal cancer, but the role of this alteration in the etiology of these diseases is unknown. O-glycans in mucin core proteins are the predominant components of the intestinal mucus, which comprises p...

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Detalhes bibliográficos
Main Authors: An, Guangyu, Wei, Bo, Xia, Baoyun, McDaniel, J. Michael, Ju, Tongzhong, Cummings, Richard D., Braun, Jonathan, Xia, Lijun
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118614/
https://ncbi.nlm.nih.gov/pubmed/17517967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061929
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