Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains

Factor H (FH) is an abundant serum glycoprotein that regulates the alternative pathway of complement-preventing uncontrolled plasma C3 activation and nonspecific damage to host tissues. Age-related macular degeneration (AMD), atypical hemolytic uremic syndrome (aHUS), and membranoproliferative glome...

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Main Authors: Pickering, Matthew C., de Jorge, Elena Goicoechea, Martinez-Barricarte, Rubén, Recalde, Sergio, Garcia-Layana, Alfredo, Rose, Kirsten L., Moss, Jill, Walport, Mark J., Cook, H. Terence, de Córdoba, Santiago Rodriguez, Botto, Marina
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2007
主題:
Brief Definitive Reports
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118613/
https://ncbi.nlm.nih.gov/pubmed/17517971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070301
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