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Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains
Factor H (FH) is an abundant serum glycoprotein that regulates the alternative pathway of complement-preventing uncontrolled plasma C3 activation and nonspecific damage to host tissues. Age-related macular degeneration (AMD), atypical hemolytic uremic syndrome (aHUS), and membranoproliferative glome...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118613/ https://ncbi.nlm.nih.gov/pubmed/17517971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070301 |
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