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The Development of Atypical Hemolytic Uremic Syndrome Depends on Complement C5

Gene variants in the alternative pathway of the complement system strongly associate with atypical hemolytic uremic syndrome (aHUS), presumably by predisposing to increased complement activation within the kidney. Complement factor H (CFH) is the major regulator of complement activation through the...

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Detalhes bibliográficos
Main Authors: de Jorge, Elena Goicoechea, Macor, Paolo, Paixão-Cavalcante, Danielle, Rose, Kirsten L., Tedesco, Franco, Cook, H. Terence, Botto, Marina, Pickering, Matthew C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014042/
https://ncbi.nlm.nih.gov/pubmed/21148255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010050451
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