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The Development of Atypical Hemolytic Uremic Syndrome Depends on Complement C5

Gene variants in the alternative pathway of the complement system strongly associate with atypical hemolytic uremic syndrome (aHUS), presumably by predisposing to increased complement activation within the kidney. Complement factor H (CFH) is the major regulator of complement activation through the...

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書誌詳細
主要な著者: de Jorge, Elena Goicoechea, Macor, Paolo, Paixão-Cavalcante, Danielle, Rose, Kirsten L., Tedesco, Franco, Cook, H. Terence, Botto, Marina, Pickering, Matthew C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Nephrology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014042/
https://ncbi.nlm.nih.gov/pubmed/21148255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010050451
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