Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

Vaccinia virus immunization provides lifelong protection against smallpox, but the mechanisms of this exquisite protection are unknown. We used polychromatic flow cytometry to characterize the functional and phenotypic profile of CD8(+) T cells induced by vaccinia virus immunization in a comparative...

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Main Authors: Precopio, Melissa L., Betts, Michael R., Parrino, Janie, Price, David A., Gostick, Emma, Ambrozak, David R., Asher, Tedi E., Douek, Daniel C., Harari, Alexandre, Pantaleo, Giuseppe, Bailer, Robert, Graham, Barney S., Roederer, Mario, Koup, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2007
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118607/
https://ncbi.nlm.nih.gov/pubmed/17535971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062363
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