PD-1 is a regulator of virus-specific CD8(+) T cell survival in HIV infection

Here, we report on the expression of programmed death (PD)-1 on human virus-specific CD8(+) T cells and the effect of manipulating signaling through PD-1 on the survival, proliferation, and cytokine function of these cells. PD-1 expression was found to be low on naive CD8(+) T cells and increased on...

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Detalhes bibliográficos
Main Authors: Petrovas, Constantinos, Casazza, Joseph P., Brenchley, Jason M., Price, David A., Gostick, Emma, Adams, William C., Precopio, Melissa L., Schacker, Timothy, Roederer, Mario, Douek, Daniel C., Koup, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118095/
https://ncbi.nlm.nih.gov/pubmed/16954372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061496
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