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PD-1 is a regulator of virus-specific CD8(+) T cell survival in HIV infection
Here, we report on the expression of programmed death (PD)-1 on human virus-specific CD8(+) T cells and the effect of manipulating signaling through PD-1 on the survival, proliferation, and cytokine function of these cells. PD-1 expression was found to be low on naive CD8(+) T cells and increased on...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118095/ https://ncbi.nlm.nih.gov/pubmed/16954372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061496 |
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