Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model

This report shows that interleukin (IL) 17–producing T helper type 17 (Th17) cells predominantly express CC chemokine receptor (CCR) 6 in an animal model of rheumatoid arthritis (RA). Th17 cells induced in vivo in normal mice via homeostatic proliferation similarly express CCR6, whereas those induci...

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Hlavní autoři: Hirota, Keiji, Yoshitomi, Hiroyuki, Hashimoto, Motomu, Maeda, Shinji, Teradaira, Shin, Sugimoto, Naoshi, Yamaguchi, Tomoyuki, Nomura, Takashi, Ito, Hiromu, Nakamura, Takashi, Sakaguchi, Noriko, Sakaguchi, Shimon
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2007
Témata:
Brief Definitive Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118525/
https://ncbi.nlm.nih.gov/pubmed/18025126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071397
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