BCL11B is required for positive selection and survival of double-positive thymocytes

Transcriptional control of gene expression in double-positive (DP) thymocytes remains poorly understood. We show that the transcription factor BCL11B plays a critical role in DP thymocytes by controlling positive selection of both CD4 and CD8 lineages. BCL11B-deficient DP thymocytes rearrange T cell...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Albu, Diana I., Feng, Dongyun, Bhattacharya, Debarati, Jenkins, Nancy A., Copeland, Neal G., Liu, Pentao, Avram, Dorina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2007
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118514/
https://ncbi.nlm.nih.gov/pubmed/17998389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070863
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