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A constant affinity threshold for T cell tolerance
T cell tolerance depends on the T cell receptor's affinity for peptide/major histocompatibility complex (MHC) ligand; this critical parameter determines whether a thymocyte will be included (positive selection) or excluded (negative selection) from the T cell repertoire. A quantitative analysis...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118488/ https://ncbi.nlm.nih.gov/pubmed/17938233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070254 |
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