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T Cell Affinity Regulates Asymmetric Division, Effector Cell Differentiation, and Tissue Pathology
The strength of interactions between T cell receptors and the peptide-major histocompatibility complex (pMHC) directly modulates T cell fitness, clonal expansion, and acquisition of effector properties. Here we show that asymmetric T cell division is an important mechanistic link between increased s...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622938/ https://ncbi.nlm.nih.gov/pubmed/23084359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.06.021 |
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