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Igκ allelic inclusion is a consequence of receptor editing
The discovery of lymphocytes bearing two light chains in mice carrying self-reactive antibody transgenes has challenged the “one lymphocyte–one antibody” rule. However, the extent and nature of allelically included cells in normal mice is unknown. We show that 10% of mature B cells coexpress both Ig...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118438/ https://ncbi.nlm.nih.gov/pubmed/17210730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061918 |
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