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The antiinflammatory activity of IgG: the intravenous IgG paradox

How high doses of intravenous IgG (IVIG) suppress autoimmune diseases remains unresolved. We have recently shown that the antiinflammatory activity of IVIG can be attributed to a minor species of IgGs that is modified with terminal sialic acids on their Fc-linked glycans. Here we propose that these...

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Autors principals: Nimmerjahn, Falk, Ravetch, Jeffrey V.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118416/
https://ncbi.nlm.nih.gov/pubmed/17227911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061788
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