Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27

The immune response to bacterial infections must be tightly controlled to guarantee pathogen elimination while preventing tissue damage by uncontrolled inflammation. Here, we demonstrate a key role of interleukin (IL)-27 in regulating this critical balance. IL-27 was rapidly induced during murine ex...

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Detalhes bibliográficos
Main Authors: Wirtz, Stefan, Tubbe, Ingrid, Galle, Peter R., Schild, Hans J., Birkenbach, Mark, Blumberg, Richard S., Neurath, Markus F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118378/
https://ncbi.nlm.nih.gov/pubmed/16880260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060471
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