Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27

The immune response to bacterial infections must be tightly controlled to guarantee pathogen elimination while preventing tissue damage by uncontrolled inflammation. Here, we demonstrate a key role of interleukin (IL)-27 in regulating this critical balance. IL-27 was rapidly induced during murine ex...

Full description

Saved in:
Bibliographic Details
Main Authors: Wirtz, Stefan, Tubbe, Ingrid, Galle, Peter R., Schild, Hans J., Birkenbach, Mark, Blumberg, Richard S., Neurath, Markus F.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
Subjects:
Brief Definitive Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118378/
https://ncbi.nlm.nih.gov/pubmed/16880260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060471
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items