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Interleukin-35 Mediates Mucosal Immune Responses That Protect Against T-Cell–Dependent Colitis

BACKGROUND & AIMS: The soluble hematopoietin receptor Epstein–Barr virus–induced protein (EBI)-3 is an immune regulator that has been associated with the pathogenesis of inflammatory bowel disease. However, the concept that EBI3 is part of an interleukin (IL)-27 heterodimer that mediates chronic...

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Detalhes bibliográficos
Main Authors: WIRTZ, STEFAN, BILLMEIER, ULRIKE, MCHEDLIDZE, TAMUNA, BLUMBERG, RICHARD S., NEURATH, MARKUS F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624892/
https://ncbi.nlm.nih.gov/pubmed/21820391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.07.040
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