Tissue expression of PD-L1 mediates peripheral T cell tolerance

Programmed death 1 (PD-1), an inhibitory receptor expressed on activated lymphocytes, regulates tolerance and autoimmunity. PD-1 has two ligands: PD-1 ligand 1 (PD-L1), which is expressed broadly on hematopoietic and parenchymal cells, including pancreatic islet cells; and PD-L2, which is restricted...

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Bibliografiska uppgifter
Huvudupphovsmän: Keir, Mary E., Liang, Spencer C., Guleria, Indira, Latchman, Yvette E., Qipo, Andi, Albacker, Lee A., Koulmanda, Maria, Freeman, Gordon J., Sayegh, Mohamed H., Sharpe, Arlene H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2006
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118286/
https://ncbi.nlm.nih.gov/pubmed/16606670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051776
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