Disparate roles of ATR and ATM in immunoglobulin class switch recombination and somatic hypermutation

Class switch recombination (CSR) and somatic hypermutation (SHM) are mechanistically related processes initiated by activation-induced cytidine deaminase. Here, we have studied the role of ataxia telangiectasia and Rad3-related protein (ATR) in CSR by analyzing the recombinational junctions, resulti...

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Autors principals: Pan-Hammarström, Qiang, Lähdesmäki, Aleksi, Zhao, Yaofeng, Du, Likun, Zhao, Zhihui, Wen, Sicheng, Ruiz-Perez, Victor L., Dunn-Walters, Deborah K., Goodship, Judith A., Hammarström, Lennart
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2006
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118080/
https://ncbi.nlm.nih.gov/pubmed/16390936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050595
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