FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells

TcRζ/CD3 ligation initiates a signaling cascade involving CD4/CD8-p56(lck), p59(fyn), and ZAP-70, as well as lymphoid downstream proteins VAV, SLP-76, and FYB/SLAP. A current question concerns the nature of the downstream binding partner(s) of FYB in T cells. In this study, using a two-hybrid screen...

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Bibliographic Details
Main Authors: Liu, Junke, Kang, Hyun, Raab, Monika, da Silva, Antonio J., Kraeft, Stine-Kathrein, Rudd, Christopher E.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC21153/
https://ncbi.nlm.nih.gov/pubmed/9671755
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