Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

T cell receptor ζ (TcRζ)/CD3 ligation initiates a signaling cascade that involves src kinases p56(lck) and ζ-associated protein 70, leading to the phosphorylation of substrates such as TcRζ, Vav, SH2-domain-containing leukocyte protein 76 (SLP-76), cbl, and p120/130. FYN binding protein (FYB or p120...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	da Silva, Antonio J., Li, Zhuwen, de Vera, Cristina, Canto, Eduardo, Findell, Paul, Rudd, Christopher E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23849/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207119/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.14.7493
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