Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

T cell receptor ζ (TcRζ)/CD3 ligation initiates a signaling cascade that involves src kinases p56(lck) and ζ-associated protein 70, leading to the phosphorylation of substrates such as TcRζ, Vav, SH2-domain-containing leukocyte protein 76 (SLP-76), cbl, and p120/130. FYN binding protein (FYB or p120...

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Detalles Bibliográficos
Main Authors: da Silva, Antonio J., Li, Zhuwen, de Vera, Cristina, Canto, Eduardo, Findell, Paul, Rudd, Christopher E.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC23849/
https://ncbi.nlm.nih.gov/pubmed/9207119
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