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An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R

Lymphocyte function-associated antigen (LFA)-1 clustering, which is needed for high avidity binding to intercellular adhesion molecule (ICAM)-1 and -2, regulates T cell motility and T cell–antigen-presenting cell (APC) conjugation. In this study, down-regulation of SKAP-55 by small interfering RNAs...

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Detalhes bibliográficos
Main Authors: Jo, Eun-Kyeong, Wang, Hongyan, Rudd, Christopher E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213273/
https://ncbi.nlm.nih.gov/pubmed/15939789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042577
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