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An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R
Lymphocyte function-associated antigen (LFA)-1 clustering, which is needed for high avidity binding to intercellular adhesion molecule (ICAM)-1 and -2, regulates T cell motility and T cell–antigen-presenting cell (APC) conjugation. In this study, down-regulation of SKAP-55 by small interfering RNAs...
Guardat en:
| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213273/ https://ncbi.nlm.nih.gov/pubmed/15939789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042577 |
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