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Variable and tissue-specific hormone resistance in heterotrimeric G(s) protein α-subunit (G(s)α) knockout mice is due to tissue-specific imprinting of the G(s)α gene
Albright hereditary osteodystrophy (AHO), an autosomal dominant disorder characterized by short stature, obesity, and skeletal defects, is associated with heterozygous inactivating mutations of GNAS1, the gene encoding the heterotrimeric G protein α-subunit (G(s)α) that couples multiple receptors to...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21142/ https://ncbi.nlm.nih.gov/pubmed/9671744 |
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