Variable and tissue-specific hormone resistance in heterotrimeric G(s) protein α-subunit (G(s)α) knockout mice is due to tissue-specific imprinting of the G(s)α gene

Albright hereditary osteodystrophy (AHO), an autosomal dominant disorder characterized by short stature, obesity, and skeletal defects, is associated with heterozygous inactivating mutations of GNAS1, the gene encoding the heterotrimeric G protein α-subunit (G(s)α) that couples multiple receptors to...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yu, Shuhua, Yu, Dawen, Lee, Eric, Eckhaus, Michael, Lee, Randy, Corria, Zakia, Accili, Domenico, Westphal, Heiner, Weinstein, Lee S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1998
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC21142/
https://ncbi.nlm.nih.gov/pubmed/9671744
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