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Subunit structure of paired helical filaments in Alzheimer's disease

The neurofibrillary tangles that occur in the brain in cases of senile dementia of the Alzheimer type contain a distinctive type of filament, the paired helical filament (PHF). We have developed a method for isolating the tangles postmortem in sufficient yield for structural study of PHFs by electro...

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Bibliografske podrobnosti
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1985
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2113596/
https://ncbi.nlm.nih.gov/pubmed/2581978
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