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The exocyclic groups of DNA modulate the affinity and positioning of the histone octamer

To investigate the nature of the chemical determinants in DNA required for nonspecific binding and bending by proteins we have created a novel DNA in which inosine–5-methylcytosine and 2,6-diaminopurine–uracil base pairs are substituted for normal base pairs in a defined DNA sequence. This procedure...

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Detaylı Bibliyografya
Asıl Yazarlar: Buttinelli, Memmo, Minnock, Andrew, Panetta, Gianna, Waring, Michael, Travers, Andrew
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1998
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC21112/
https://ncbi.nlm.nih.gov/pubmed/9671714
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