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Histone octamer rearranges to adapt to DNA unwrapping
Nucleosomes, the basic unit of chromatin, package and regulate expression of eukaryotic genomes. Although the structure of the intact nucleosome has been studied, little is known about structures of its partially unwrapped, transient intermediates. In this study, we present 9 cryo EM structures of d...
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| 發表在: | Nat Struct Mol Biol |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800490/ https://ncbi.nlm.nih.gov/pubmed/29323273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-017-0005-5 |
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