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Histone octamer rearranges to adapt to DNA unwrapping

Nucleosomes, the basic unit of chromatin, package and regulate expression of eukaryotic genomes. Although the structure of the intact nucleosome has been studied, little is known about structures of its partially unwrapped, transient intermediates. In this study, we present 9 cryo EM structures of d...

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Détails bibliographiques
Publié dans:Nat Struct Mol Biol
Auteurs principaux: Bilokapic, Silvija, Strauss, Mike, Halic, Mario
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800490/
https://ncbi.nlm.nih.gov/pubmed/29323273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-017-0005-5
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