The exocyclic groups of DNA modulate the affinity and positioning of the histone octamer

To investigate the nature of the chemical determinants in DNA required for nonspecific binding and bending by proteins we have created a novel DNA in which inosine–5-methylcytosine and 2,6-diaminopurine–uracil base pairs are substituted for normal base pairs in a defined DNA sequence. This procedure...

Full description

Saved in:
Bibliographic Details
Main Authors: Buttinelli, Memmo, Minnock, Andrew, Panetta, Gianna, Waring, Michael, Travers, Andrew
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC21112/
https://ncbi.nlm.nih.gov/pubmed/9671714
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items