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Epigenetic Effects of the Continuous Exposure to Peroxisome Proliferator WY-14,643 in Mouse Liver are Dependent upon Peroxisome Proliferator Activated Receptor α

Peroxisome proliferators are potent rodent liver carcinogens that act via a non-genotoxic mechanism. The mode of action of these agents in rodent liver includes increased cell proliferation, decreased apoptosis, secondary oxidative stress and other events; however, it is not well understood how pero...

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Detalhes bibliográficos
Main Authors: Pogribny, Igor P., Tryndyak, Volodymyr P., Woods, Courtney G., Witt, Sarah E., Rusyn, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111058/
https://ncbi.nlm.nih.gov/pubmed/17586532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2007.05.004
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