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Reinitiation of DNA synthesis in senescent human fibroblasts upon fusion with cells of unlimited growth potential
Postreplicative, "senescent" human fibroblasts were fused to HeLa or to SV-40 transformed human fibroblasts with Sendai virus. DNA synthesis was reinitiated in senescent nuclei in a high proportion of the heterodikaryons. The [3H]thymidine labeling index of senescent fibroblast nuclei in h...
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| Formato: | Artigo |
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| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
1975
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2109544/ https://ncbi.nlm.nih.gov/pubmed/1150745 |
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