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Reinitiation of DNA synthesis in senescent human fibroblasts upon fusion with cells of unlimited growth potential

Postreplicative, "senescent" human fibroblasts were fused to HeLa or to SV-40 transformed human fibroblasts with Sendai virus. DNA synthesis was reinitiated in senescent nuclei in a high proportion of the heterodikaryons. The [3H]thymidine labeling index of senescent fibroblast nuclei in h...

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Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1975
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2109544/
https://ncbi.nlm.nih.gov/pubmed/1150745
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