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Expression of c-fos and AP-1 activity in senescent human fibroblasts is not sufficient for DNA synthesis
Human fibroblasts have a limited replicative life span when maintained in culture after which they become unresponsive to treatment with mitogens, a phenomenon most commonly called senescence. Experiments indicating that serum does not induce expression of the c-fos proto- oncogene in senescent fibr...
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| Format: | Artigo |
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| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
1992
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2289766/ https://ncbi.nlm.nih.gov/pubmed/1469041 |
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