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Expression of c-fos and AP-1 activity in senescent human fibroblasts is not sufficient for DNA synthesis

Human fibroblasts have a limited replicative life span when maintained in culture after which they become unresponsive to treatment with mitogens, a phenomenon most commonly called senescence. Experiments indicating that serum does not induce expression of the c-fos proto- oncogene in senescent fibr...

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Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1992
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289766/
https://ncbi.nlm.nih.gov/pubmed/1469041
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