Mast cell tumor necrosis factor α production is regulated by MEK kinases

Mast cells synthesize and secrete specific cytokines and chemokines which play an important role in allergic inflammation. Aggregation of the high-affinity Fc receptor (FcɛRI) for immunoglobulin E (IgE) in MC/9 mouse mast cells stimulates the synthesis and secretion of tumor necrosis factor α (TNF-α...

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Detalhes bibliográficos
Main Authors: Ishizuka, Tamotsu, Terada, Naohiro, Gerwins, Pär, Hamelmann, Eckard, Oshiba, Akihiro, Fanger, Gary R., Johnson, Gary L., Gelfand, Erwin W.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21054/
https://ncbi.nlm.nih.gov/pubmed/9177222
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