Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice

Dopamine (DA) cell replacement therapy in Parkinson disease (PD) can be achieved using human fetal mesencephalic tissue; however, limited tissue availability has hindered further developments. Embryonic stem cells provide a promising alternative, but poor survival and risk of teratoma formation have...

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Главные авторы: Parish, Clare L., Castelo-Branco, Gonçalo, Rawal, Nina, Tonnesen, Jan, Sorensen, Andreas Toft, Salto, Carmen, Kokaia, Merab, Lindvall, Olle, Arenas, Ernest
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2007
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2104477/
https://ncbi.nlm.nih.gov/pubmed/18060047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32273
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